Marvel’s Deadpool VR Brings Wade Wilson to Life in a New Way (Literally As Him) | Review

After getting a chance to play Marvel’s Deadpool VR back in June at Summer Game Fest, I actually got to get my hands on the game as it looked its full launch in the eye on November 18.

The same week Marvel’s Deadpool VR launched, it also got a nomination for Best VR/AR Game at the upcoming Game Awards on December 11.

The game’s launch is a great excuse to scour for great Black Friday or Cyber Monday deals. The Meta Quest 3 would be a great addition under the tree this holiday season for the gamer or comic book fan in your life who has been wanting to jump into VR.

Note: VR is a newer avenue of gaming for me, so I want to preface that my review may reflect that! This review will also be spoiler free. 

“Contracted by Mojo, with the promise of making money, like a lot of money, Deadpool sets out to capture villains from the Marvel Universe,” the game’s official description reads. “The Merc with the Mouth soon realizes he shouldn’t have so hastily signed the contract. Will he survive or thrive in his journey to become the Mojoverse’s most famous interdimensional streaming star?”

Deadpool VR
Developed by:
Twisted Pixels and Oculus Studios
Platforms: Meta Quest 3 and 3S
Release date: November 18, 2025

Marvel’s Deadpool VR was developed by Twisted Pixels and Oculus Studios, and the team worked closely in collaboration with Marvel Games on the VR-exclusive title.

A New Voice as Wade Wilson

Our favorite anti-hero Wade Wilson is voiced by Neil Patrick Harris, who developers said in June was part of the effort to bring their own “unique spin on Deadpool” to life.

“So our own voice, our own actor, our own lighting, but in a way that is familiar for people. That way we can bring some new, but without being jarring,” Lead Designer Phil Therien told me at Summer Game Fest in June.

And I personally feel like Twisted Pixels and Harris accomplished that. There is a ton of dialogue in this game, from classic fourth wall breaking, many many many references, and endless commentary (even if you happen to be talking to friends IRL while playing). Deadpool’s charm, to me, has always been that he was always spouting off in the comic, and becoming fully immersed in it was just as engaging as I thought it would be.

Developers carved out the world around Wade with as much care and enthusiasm as they did with the titular character. We also got John Leguizamo as Mojo and the Jeffrey Combs as Mojo’s chief henchman, Major Domo, along with the talent from Christopher Sabat (Vegeta, All Might, a billion more), Brina Palencia (Tony Tony Chopper in One Piece, Mineta in My Hero, Holo in Spice and Wolf), J Michael Tatum (Erwin in Attack on Titan, Eneru in One Piece), Michael Rosenbaum (Flash/Barry Allen and Wally West, and more).

“I think once it all came down to it, Neil was perfect,” Therien said in the chat during Play Days. “We have a lot of writers that have written a lot of the dialog for the game, including Joe Kelly who was one of the Deadpool writers in the comics. So when Neil came in and read the lines that were written for him, it was just meant to be.”

Gameplay

Deadpool’s variety of weaponry is available for you to wield, whether its his iconic double pistols or double katanas, grenades, his grapple gun, or even his own severed limbs that can be thrown to stun enemies.

As a new-to-VR player, it did take me some time for cycling through my weapons i.e. pulling the katanas from my shoulders, drawing my double pistols from my thighs, the grapple gun from behind my back. There are also settings that allow you to physically remap the holster locations, and you can set your grapple to quick swap.

Combat rooms, particularly through the start of the game, helped me get used to the overall fighting focus of the game, and you’ll have your fair share of faceless henchmen to decimate, allowing you to unlock weapons and cosmetics as you end their lives in over-the-top ways. You’ll also have the chance to scour levels for collectables in the form of comic book covers featuring the titular Merc with a Mouth.

Boss battles also include quick time events to really engage you in what feels like authentic superhero choreography, using all the weapons in your arsenal to do so. There are also a fair number of VR puzzles to traverse through, and the use of the grapple gun really engages more depth across your surroundings.

Combat can be intense and overwhelming, and the game does offer a variety of comfort settings, allowing you to adjust them to help ease issues around motion sickness or the propensity for it with the vignette settings which darken the edges of the screen, as well as snap turning and camera shake options.

There are also three difficulty levels: VR Newbie, VR Curious and VR Hero. The difficulty settings will also pre-select comfort settings to assist in the adjustments as needed.

Takeaways

The VR combat can be intense, but the comfort settings available can help with offsetting the overwhelm for newer players (like me!).

Twisted Pixel and the team did a fabulous job of not just bringing Wade Wilson to life, but also the many Marvel characters that make an appearance in the game and the world within so well. The game in VR really forces the world to come alive in a way the traditional gaming format can’t replicate — whether you’re trying to dodge Mephisto’s blistering attacks or fully beheaded and watching your own body do your own bidding.

Final Thoughts

VR has been a newer endeavor in my gaming journey and 'Marvel's Deadpool VR' was the most intense game I've jumped into so far. The combat was very intense for me, but comfort settings allowed me to figure out a configuration that worked best for me. And, in the end, if I had to do a boss fight a few times, I got to experience the immersive superhero choreography that I was just used to reading on the page/seeing on the big screen. I was in awe of the world they built and the characters they brought to life, and genuinely enjoyed the non-stop and ongoing commentary from Wade. NPH's Wade was also a massive delight.
Katy Barber
Katy Barberhttp://www.kakebytes.com
Editor in Chief. Early access and cozy game connoisseur. Moira main.

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VR has been a newer endeavor in my gaming journey and 'Marvel's Deadpool VR' was the most intense game I've jumped into so far. The combat was very intense for me, but comfort settings allowed me to figure out a configuration that worked best for me. And, in the end, if I had to do a boss fight a few times, I got to experience the immersive superhero choreography that I was just used to reading on the page/seeing on the big screen. I was in awe of the world they built and the characters they brought to life, and genuinely enjoyed the non-stop and ongoing commentary from Wade. NPH's Wade was also a massive delight. Marvel’s Deadpool VR Brings Wade Wilson to Life in a New Way (Literally As Him) | Review